Imaging cerebral blood flow through the intact rat skull with temporal laser speckle imaging

• DOI: 10.1364/ol.31.001824
• Publication Date: 2006-05-25T18:38:45Z
• Authors: Pengcheng Li; Songlin Ni; Li Zhang; Shaoqun Zeng; Qingming Luo
• Keywords: Speckle imaging; Speckle noise

We discovered that laser speckle temporal contrast analysis (LSTCA) is able to access the two-dimensional (2D) cerebral blood flow velocity and vessel structure through intact rat skull. It demonstrated LSTCA can significantly suppress influence of from stationary structure, such as skull, thus reveal morphology vessels images recorded