Needle-based refractive index measurement using low-coherence interferometry

• DOI: 10.1364/ol.32.000385
• Publication Date: 2007-01-25T18:39:17Z
• Authors: Adam M. Zysk; Steven G. Adie; Julian J. Armstrong; Matthew S. Leigh; Alexandre Paduch; David D. Sampson; Freddy T. Nguyen; Stephen A. Boppart
• Keywords: White light interferometry; Optical path

We present a novel needle-based device for the measurement of refractive index and scattering using low-coherence interferometry. Coupled to sample arm an optical coherence tomography system, detects response of, path length through, residing in fixed-width channel. report use make near-infrared measurements tissues materials with known properties. The could be used exploit variations tissue medical biological diagnostics accessible by needle insertion.