Programmable, high-speed, adaptive optics partially confocal multi-spot ophthalmoscope using a digital micromirror device

• DOI: 10.1364/ol.480688
• Publication Date: 2023-01-03T14:00:34Z
• Authors: Soohyun Lee; Stacey S. Choi; Ratheesh K. Meleppat; Robert J. Zawadzki; Nathan Doble
• Keywords: Digital micromirror device; Spatial light modulator; Frame rate

A high-speed, adaptive optics partially confocal multi-spot ophthalmoscope (AO-pcMSO) using a digital micromirror device (DMD) in the illumination channel and fast 2D CMOS camera is described. The synchronized with DMD allowing projection of multiple, simultaneous AO-corrected spots onto human retina. Spatial filtering on each raw retinal image before reconstruction works as an array virtual pinholes. frame acquisition rate 250 fps achieved by applying this parallel scheme. contrast improves 2-3 fold when compared to standard flood architecture. Partially images retina show cone rod photoreceptors over range eccentricities.