The Reality of Pervasive Transcription

• DOI: 10.1371/journal.pbio.1000625
• Publication Date: 2011-07-12T16:42:15Z
• Authors: Michael B. Clark; Paulo P. Amaral; Felix J. Schlesinger; Marcel E. Dinger; Ryan J. Taft; John L. Rinn; Chris P. Ponting; Peter F. Stadler; Kevin V. Morris; Antonin Morillon; Joel S. Rozowsky; Mark B. Gerstein; Claes Wahlestedt; Yoshihide Hayashi...; Piero Carninci; Thomas R. Gingeras; John S. Mattick
• Keywords: 2800 Neuroscience; Epigenomics; DNA, Complementary; 1300 Biochemistry; Transcription, Genetic; Evolution; QH301-705.5; [SDV]Life Sciences [q-bio]; Expression; Genetics and Molecular Biology; Long noncoding RNAs; 1100 Agricultural and Biological Sciences; 03 medical and health sciences; 616; Databases, Genetic; Animals; Humans; Biology (General); Oligonucleotide Array Sequence Analysis; Expressed Sequence Tags; Mammals; 0303 health sciences; Genome; Sequence Analysis, RNA; 2400 Immunology and Microbiology; [SDV] Life Sciences [q-bio]; Differentiation; Perspective; Tiling arrays; Artifacts; Reveal

Despite recent controversies, the evidence that the majority of the human genome is transcribed into RNA remains strong.