Foundations of circadian medicine

• DOI: 10.1371/journal.pbio.3001567
• Publication Date: 2022-03-24T21:24:32Z
• Authors: Achim Kramer; Tanja Lange; Claudia Spies; Anna-Marie Finger; Daniela Berg; Henrik Oster
• Keywords: Chronobiology

The circadian clock is an evolutionarily highly conserved endogenous timing program that structures physiology and behavior according to the time of day. Disruption rhythms associated with many common pathologies. emerging field medicine aims exploit mechanisms clock–disease interaction for clinical diagnosis, treatment, prevention. In this Essay, we outline principle approaches medicine, highlight development in selected areas, point out open questions challenges. Circadian has unambiguous health benefits over standard care but rarely utilized. It biology become integrated part translational research.