Noise during Rest Enables the Exploration of the Brain's Dynamic Repertoire

• DOI: 10.1371/journal.pcbi.1000196
• Publication Date: 2008-10-09T17:09:53Z
• Authors: Anandamohan Ghosh; Y. Rho; A. R. McIntosh; R. Kötter; V. K. Jirsa
• Keywords: Communication noise; Rest (music); Dynamic functional connectivity; Nerve net; Magnetoencephalography

Traditionally brain function is studied through measuring physiological responses in controlled sensory, motor, and cognitive paradigms. However, even at rest, the absence of overt goal-directed behavior, collections cortical regions consistently show temporally coherent activity. In humans, these resting state networks have been shown to greatly overlap with functional architectures present during consciously directed activity, which motivates interpretation rest activity as day dreaming, free association, stream consciousness, inner rehearsal. monkeys, it has though that similar fluctuations are deep anesthesia when there no consciousness. Here, we comparable emerge from a stability analysis network dynamics using biologically realistic primate connectivity, although anatomical information alone does not identify network. We specifically demonstrate noise time delays via propagation along connecting fibres essential for emergence default The spatiotemporal evolves on multiple temporal scales displays intermittent neuroelectric oscillations fast frequency regimes, 1–100 Hz, commonly observed electroencephalographic magnetoencephalographic recordings, well hemodynamic ultraslow <0.1 magnetic resonance imaging. combination structure creates space–time neural enables explore various configurations representing its dynamic repertoire.