Sex-Specific Crossover Distributions and Variations in Interference Level along Arabidopsis thaliana Chromosome 4

• DOI: 10.1371/journal.pgen.0030106
• Publication Date: 2007-06-27T12:30:39Z
• Authors: Jan Drouaud; Raphaël Mercier; Liudmila Chelysheva; Aurélie Bérard; Matthieu Falque; Olivier Martin; Vanessa Zanni; Dominique Brunel; Christine Mézard
• Keywords: Synaptonemal complex; Meiocyte; Chromosomal crossover

In many species, sex-related differences in crossover (CO) rates have been described at chromosomal and regional levels. this study, we determined the CO distribution along entire Arabidopsis thaliana Chromosome 4 (18 Mb) male female meiosis, using high density genetic maps built on large backcross populations (44 markers, >1,300 plants). We observed dramatic between map lengths that were calculated as 88 cM 52 cM, respectively. This difference is remarkably parallel to total synaptonemal complex measured meiocytes by immunolabeling of ZYP1 (a component complex). Moreover, landscapes clearly different: particular, both ends map, higher (up 4-fold mean value), whereas equal or even below average. unique material gave us opportunity perform a detailed analysis interference meiosis. The number COs per chromosome distances them departs from randomness. Strikingly, level (measured coincidence) varied significantly meiosis was correlated physical distance COs. significance finding relevance current models discussed.