The Relationship between Cerebral Glucose Metabolism and Age: Report of a Large Brain PET Data Set

• DOI: 10.1371/journal.pone.0051517
• Publication Date: 2012-12-20T17:18:48Z
• Authors: Xiaoyan Shen; Huafeng Liu; Zhenghui Hu; Hongjie Hu; Pengcheng Shi
• Keywords: Statistical parametric mapping; Carbohydrate Metabolism

Cerebral glucose metabolism is a reliable index of neural activity and may provide evidence for brain function in healthy adults. We studied the correlation between cerebral age under resting-state both sexes with position emission tomography. Statistical test effect on was performed using statistical parametric mapping software voxel-by-voxel approach ( family wise error corrected, -voxel threshold). The subjects consisted 108 females (mean S.D. = 4510 years) 126 males 4911 years). showed here that frontal temporal lobes decreased significantly normal aging. caudate bilaterally negative males, but not females. Few regions were shown an increased age. Although mechanisms aging are still unknown, map areas susceptible to described this report.