The Cost-Effectiveness of Wound-Edge Protection Devices Compared to Standard Care in Reducing Surgical Site Infection after Laparotomy: An Economic Evaluation alongside the ROSSINI Trial

• DOI: 10.1371/journal.pone.0095595
• Publication Date: 2014-04-19T00:10:32Z
• Authors: Adrian Gheorghe; Tracy E. Roberts; Thomas D. Pinkney; David C. Bartlett; Dion Morton; Melanie Calvert
• Keywords: Economic Evaluation; Incremental cost-effectiveness ratio

Background Wound-edge protection devices (WEPDs) have been used in surgery for more than 40 years to reduce surgical site infection (SSI). No economic evaluation of WEPDs against any comparator has ever conducted. The aim the paper was assess whether are cost-effective reducing SSI compared standard care alone United Kingdom. Methods and Findings An conducted alongside ROSSINI trial. study perspective that UK National Health Service time horizon 30 days post-operatively. 21 hospitals. 760 patients undergoing laparotomy were randomised either WEPD or 735 included primary analysis. main outcome cost-effectiveness based on incremental cost (£) per quality adjusted life year (QALY) gained. Patients arm accessed health worth £5,420 average gained 0.02131 QALYs, £5,130 0.02133 QALYs arm. strategy costly equally effective care, but there significant uncertainty around costs QALYs. findings robust a range sensitivity analyses. Conclusions There is no evidence suggest can be considered device SSI. Their continued use waste limited resources.