Macular Pigment Optical Density Measured by Heterochromatic Modulation Photometry

• DOI: 10.1371/journal.pone.0110521
• Publication Date: 2014-10-29T18:30:57Z
• Authors: Cord Huchzermeyer; Juliane Schlomberg; Ulrich Welge-Lüssen; Tos T. J. M. Bere...; Joel Pokorny; Jan Kremers
• Keywords: Densitometer

Purpose To psychophysically determine macular pigment optical density (MPOD) employing the heterochromatic modulation photometry (HMP) paradigm by estimating 460 nm absorption at central and peripheral retinal locations. Methods For HMP measurements, two lights (B: R: 660 nm) were presented in a test field modulated counterphase medium or high frequencies. The contrasts of varied tandem to flicker detection thresholds. Detection thresholds measured for different R:B ratios. ratio with minimal sensitivity (maximal threshold) is point equiluminance. Measurements performed 25 normal subjects (11 male, 14 female; age: 30±11 years, mean ± sd) using an eight channel LED stimulator Maxwellian view optics. results compared those from published techniques – one based on (Macular Densitometer) other fundus reflectometry (MPR). Results We able estimate MPOD modified theoretical model that was fitted data. resultant MPODHMP values correlated significantly MPODMPR MPODHFP obtained 0.25° 0.5° eccentricity. Conclusions flicker-based method measurements taken constant chromaticity luminance. data can be well fit allows all points contribute photometric equality estimate. Therefore, we think may useful basic clinical vision experiments.