Inhibition of Bone Morphogenetic Protein Signal Transduction Prevents the Medial Vascular Calcification Associated with Matrix Gla Protein Deficiency

• DOI: 10.1371/journal.pone.0117098
• Publication Date: 2015-01-20T18:47:58Z
• Authors: Rajeev Malhotra; Megan F. Burke; Trejeeve Martyn; Hannah R. Shakartzi; Timothy E. Thayer; Caitlin O’Rourke; Pingcheng Li; Matthias Derwall; Ester Spagnolli; Starsha A. Kolodziej; Konrad Hoeft; Claire Mayeur; Pawina Jiramongko...; Ravindra Kumar; Emmanuel S. Buys; Paul B. Yu; Kenneth D. Bloch; Donald B. Bloch
• Keywords: Mice, Knockout; 0301 basic medicine; 570; Extracellular Matrix Proteins; Matrix Gla Protein; Science; Q; Calcium-Binding Proteins; R; 610; Fluorescent Antibody Technique; Mice; 03 medical and health sciences; Pyrimidines; Bone Morphogenetic Proteins; Medicine; Animals; Pyrazoles; Vascular Calcification; Research Article; Signal Transduction

PLoS one 10(1), e0117098 (2015). doi:10.1371/journal.pone.0117098<br/>Published by PLoS, Lawrence, Kan.<br/>