Surgical Management for Early-Stage Bilateral Breast Cancer Patients in China

• DOI: 10.1371/journal.pone.0122692
• Publication Date: 2015-04-15T18:50:26Z
• Authors: Jia-jian Chen; Nai-si Huang; Jing-yan Xue; Chen-lian Quan; Yu-long Tan; Guang-yu Liu; Zhi-min Shao; Jiong Wu
• Keywords: Lobular carcinoma

Background The aim of this study was to investigate the current surgical management strategy for bilateral breast cancer (BBC) patients and assess changes in China. Methods This is a retrospective review all with early-stage BBC who underwent treatment at Fudan University Shanghai Cancer Center between June 2007 2014. Results A total 15,337 primary were identified. Of these patients, 218 (1.5%) suffered from synchronous (sBBC), 296 (2.0%) metachronous (mBBC). Patients lobular carcinoma component, those estrogen receptor-positive cancer, an accompanying sclerosing adenosis affected tended develop BBC. rates mastectomy, conserving therapy, reconstruction, combined surgeries 86.2%, 6.4%, 3.7%, respectively, sBBC 81.1%, 4.4%, 3.0%, 11.5%, mBBC. interval cancers, age first diagnosis histopathological type, stage have significant impacts on choice surgery Conclusions Bilateral mastectomy dominant China, despite increased application reconstruction observed recent years. prosthetic ideal sBBC. Chinese surgeons should take responsibility patient education inform their about options.