Endovascular Management of Post-Irradiated Carotid Blowout Syndrome

• DOI: 10.1371/journal.pone.0139821
• Publication Date: 2015-10-06T18:05:48Z
• Authors: Feng-Chi Chang; Chao-Bao Luo; Jiing-Feng Lirng; Chung-Jung Lin; Han-Jui Lee; Chih-Chun Wu; Sheng-Che Hung; Wan-Yuo Guo
• Keywords: Adult; Carotid Artery Diseases; Male; Science; Blood Vessel Prosthesis Implantation; 03 medical and health sciences; 0302 clinical medicine; Humans; Aged; Retrospective Studies; Aged, 80 and over; Q; Endovascular Procedures; R; Middle Aged; Embolization, Therapeutic; 3. Good health; Treatment Outcome; Head and Neck Neoplasms; Carotid Artery, External; Medicine; Female; Stents; Research Article

Purpose To retrospectively evaluate the clinical and technical factors related to outcomes of endovascular management in patients with head-and-neck cancers associated post-irradiated carotid blowout syndrome (PCBS). Materials Methods Between 2000 2013, 96 PCBS underwent management. The 40 pathological lesions located external artery were classified as group 1 treated embolization. other 56 trunk divided into 2 groups follows: 2A comprised 38 embolization, 2B 18 stent-graft placement. Fisher's exact test was used examine methods, severities, postprocedural diseases predictors outcomes. Results Technical success immediate hemostasis achieved all patients. results according methods (group vs 2B) complication (1/40[2.5%] 9/38[23.7%] 9/18[50.0%], P = 0.0001); rebleeding (14/40[35.0%] 5/38[13.2%] 7/18[38.9%]), 0.0435). severity (acute ongoing PCBS) (15/47[31.9%] 4/49[8.2%], 0.0035); (18/47[38.3%] 8/49[16.3%], 0.0155). post-procedural disease (regressive progressive change) alive (14/21[66.7%] 8/75[10.7%], P<0.0001); survival time (34.1±30.6[0.3–110] 3.6±4.0[0.07–22] months, P<0.0001). Conclusion can be improved by taking embolization a prior way treatment, performing intervention slight aggressive disease.