In Vivo MRI Measurement of Spinal Cord Displacement in the Thoracolumbar Region of Asymptomatic Subjects with Unilateral and Sham Straight Leg Raise Tests

• DOI: 10.1371/journal.pone.0155927
• Publication Date: 2016-06-02T13:38:44Z
• Authors: M. Rade; M. Könönen; J. Marttila; M. Shacklock; R. Vanninen; M. Kankaanpää; O. Airaksinen
• Keywords: Adult; Male; Science; Movement; Spinal Cord Diseases; Thoracic Vertebrae; Pelvis; 03 medical and health sciences; 0302 clinical medicine; Humans; Knee; Leg; Hip; Lumbar Vertebrae; Q; R; Magnetic Resonance Imaging; 3. Good health; Spinal Nerves; Spinal Cord; SLR, Sciatica, low back pain, MR, Spinal cord, nerve root; Medicine; Female; Research Article

Normal displacement of the conus medullaris with unilateral and bilateral SLR has been quantified and the "principle of linear dependence" has been described.Explore whether previously recorded movements of conus medullaris with SLRs are i) primarily due to transmission of tensile forces transmitted through the neural tissues during SLR or ii) the result of reciprocal movements between vertebrae and nerves.Controlled radiologic study.Ten asymptomatic volunteers were scanned with a 1.5T magnetic resonance (MR) scanner using T2 weighted spc 3D scanning sequences and a device that permits greater ranges of SLR. Displacement of the conus medullaris during the unilateral and sham SLR was quantified reliably with a randomized procedure. Conus displacement in response to unilateral and sham SLRs was quantified and the results compared.The conus displaced caudally in the spinal canal by 3.54±0.87 mm (mean±SD) with unilateral (p≤.001) and proximally by 0.32±1.6 mm with sham SLR (p≤.542). Pearson correlations were higher than 0.99 for both intra- and inter-observer reliability and the observed power was 1 for unilateral SLRs and 0.054 and 0.149 for left and right sham SLR respectively.Four relevant points emerge from the presented data: i) reciprocal movements between the spinal cord and the surrounding vertebrae are likely to occur during SLR in asymptomatic subjects, ii) conus medullaris displacement in the vertebral canal with SLR is primarily due to transmission of tensile forces through the neural tissues, iii) when tensile forces are transmitted through the neural system as in the clinical SLR, the magnitude of conus medullaris displacement prevails over the amount of bone adjustment.