Human Exposure to Anaplasma phagocytophilum in Two Cities of Northwestern Morocco

• DOI: 10.1371/journal.pone.0160880
• Publication Date: 2016-08-17T18:02:23Z
• Authors: Sarah Elhamiani K...; Hamid Sahibi; Mony Hing; Ismail Alaoui Mou...; Hamid El Amri; Mohammed Benajiba; Malika Kachani; Luc Duchateau; Sylvie Daminet
• Keywords: Adult; Male; 0301 basic medicine; Adolescent; Science; Blood Donors; LYME BORRELIOSIS; HUMAN GRANULOCYTIC EHRLICHIOSIS; CHINA; FORESTRY RANGERS; Young Adult; 03 medical and health sciences; Dogs; Risk Factors; Seroepidemiologic Studies; Zoonoses; Medicine and Health Sciences; Animals; Humans; Cities; TICK; BABESIA-MICROTI; POLAND; SEROPREVALENCE; Q; R; Ehrlichiosis; SEROLOGICAL EVIDENCE; Middle Aged; Antibodies, Bacterial; NORTHEASTERN; 3. Good health; Morocco; BLOOD-DONORS; Animals, Domestic; Immunoglobulin G; Medicine; Female; Research Article; Anaplasma phagocytophilum

Anaplasma phagocytophilum is an emerging tick-borne zoonosis with extensive increased interest. Epidemiological data are available in several regions of the USA, Europe and Asia in contrast to other parts of the world such as North Africa. Blood samples of 261 healthy individuals divided in two groups i.e., dog handlers and blood donors were analysed. Indirect immunofluorescent assay using a commercial kit was performed to detect specific A. phagocytophilum IgG. Two dilutions were used to assess the prevalence of seroreactive samples. Demographic variables were assessed as potential risk factors using exact logistic regression. Seropositivity rates reached 37% and 27% in dog handlers and 36% and 22% in blood donors. No statistically significant differences were found in the prevalence rates between the two groups. Analysis of risk factors such as gender, age groups, outdoor activities, self-reported previous exposure to ticks, or contact with domestic animals (dogs, cats, ruminants and horses) did not shown any significant difference. A. phagocytophilum exposure was common in both high-risk population and blood donors in Morocco.