Characteristics of Severe Retinopathy of Prematurity in Infants with Birth Weight above 1500 Grams at a Referral Center in Turkey

• DOI: 10.1371/journal.pone.0161692
• Publication Date: 2016-08-22T13:33:55Z
• Authors: Murat Gunay; Gokhan Celik; Abdulhamit Tuten; Guner Karatekin; Handan Bardak; Fahri Ovali
• Keywords: Male; Turkey; Science; Angiogenesis Inhibitors; Severity of Illness Index; 03 medical and health sciences; 0302 clinical medicine; Intensive Care Units, Neonatal; Humans; Retinopathy of Prematurity; Retrospective Studies; Laser Coagulation; Q; R; Infant, Newborn; Infant; Infant, Low Birth Weight; 3. Good health; Bevacizumab; Intravitreal Injections; Medicine; Female; Infant, Premature; Research Article

To demonstrate the clinical characteristics and treatment outcomes of severe retinopathy prematurity (ROP) in preterm infants with birth weight (BW) above 1500 g Turkey.A retrospective review 5920 ROP records was performed Zeynep Kamil Maternity Children's Diseases Training Research Hospital. The were obtained from center same institute between 2011 2016. data comprised demographic including, gestational age, BW, systemic risk factors, zone stage ROP, type, modality, inborn/outborn status babies.A total 36 (71 eyes) BW> retrieved. There 30 (83.3%) type 1 6 (16.7%) aggressive posterior (APROP). 3 (8.3%) born at our hospital whereas 33 (91.7%) referred outer private neonatal intensive care unit (NICU) centers. Zone I APROP detected during initial screening. 21 (58.3%) underwent laser while 15 (41.7%) received intravitreal bevacizumab (IVB) injections. No unfavorable structural outcome observed following either modality.Severe may occur heavier infants. Laser IVB injections useful selected cases. Presence first examination suggests an earlier screening babies. Standardization NICU centers as well establishing a national protocol is necessary Turkey.