Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015

• DOI: 10.1371/journal.pone.0170253
• Publication Date: 2017-01-20T19:59:21Z
• Authors: Hongmei Sun; Guanhua Xue; Chao Yan; Shaoli Li; Hanqing Zhao; Yanling Feng; Liqiong Wang
• Keywords: 0301 basic medicine; China; Science; Q; R; Mycoplasma pneumoniae; 3. Good health; 03 medical and health sciences; Genes, Bacterial; Drug Resistance, Bacterial; Medicine; Humans; Child; Research Article

The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction-positive specimens (331 were previously reported and 149 newly reported) collected from pediatric patients in Beijing, China, between 2003 2015 analyzed. Genotype M4-5-7-2/P1 the most prevalent across 13-year study period, although isolation mutation rates for this genotype varied periods 2003–2007, 2008–2013, 2014–2015. In addition, there was a close association M4-5-7-2 macrolide resistance.