Decline in lung function rather than baseline lung function is associated with the development of metabolic syndrome: A six-year longitudinal study

• DOI: 10.1371/journal.pone.0174228
• Publication Date: 2017-03-27T16:40:30Z
• Authors: Soo Kyoung Kim; Ji Cheol Bae; Jong-Ha Baek; Jae Hwan Jee; Kyu Yeon Hur; Moon-Kyu Lee; Jae Hyeon Kim
• Keywords: Vital capacity

This study was conducted to investigate whether baseline lung function or change in is associated with the development of metabolic syndrome (MS) Koreans. We analyzed clinical and laboratory data from 3,768 Koreans aged 40-60 years who underwent medical check-ups over a six-year period between 2006 2012. calculated percent forced vital capacity (FVC) expiratory volume 1 s (FEV1) period. tested for an association during follow-up MS. The 533 subjects (14.1%) developed MS after follow-up. FVC FEV1 were not different six subject without years. higher than that did develop (-5.75 [-10.19 --1.17], -3.29 [-7.69-1.09], respectively, P = 0.001). adjusting age, sex, body mass index (BMI), glucose, HDL, triglyceride, waist circumferences (WC), systolic blood pressure. However, these significant BMI WC (P 0.306). greater development, predominantly due obesity abdominal obesity. prospective needed determine relationship decline