Factors associated with life-sustaining treatment restriction in a general intensive care unit

• DOI: 10.1371/journal.pone.0181312
• Publication Date: 2017-07-18T13:35:08Z
• Authors: Stein Arve Skjaker; Henrik Hoel; Vegard Dahl; Knut Stavem
• Keywords: Male; Science; Q; R; Middle Aged; 3. Good health; 12. Responsible consumption; Hospitals, University; Intensive Care Units; 03 medical and health sciences; Patient Admission; 0302 clinical medicine; Withholding Treatment; Medicine; Humans; Artikkel; VDP::Medisinske Fag: 700; Female; Research Article; Aged

Purpose Few previous studies have investigated associations between clinical variables available after 24 hours in the intensive care unit (ICU), including Charlson Comorbidity Index (CCI), and decisions to restrict life-sustaining treatment. The aim of this study was identify factors associated with treatment restriction explore if CCI contributes explaining ICU at a university hospital Norway from 2007 2009. Methods Patients' Simplified Acute Physiology Score II (SAPS II), age, sex, type admission, length stay prior being admitted were recorded. We retrospectively registered for all patients based on medical records index stay. A multivariable logistic regression analysis used assess during Results included 936 patients, comprising 685 (73%) medical, 204 (22%) unscheduled 47 (5%) scheduled surgical patients. Treatment experienced by 241 (26%) their that significantly older age (odds ratio [OR] = 1.48 per 10 years, 95% confidence interval [CI] 1.28–1.72 years), higher SAPS (OR 1.05, CI 1.04–1.07) values relative reference 0: 2 2.08, 1.20–3.61) CCI≥3 2.72, 1.65–4.47). Conclusions In analysis, greater illness severity h comorbidity admission independently subsequent restriction. score contributed additional information independent rating.