Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China

• DOI: 10.1371/journal.pone.0183083
• Publication Date: 2017-08-15T13:32:23Z
• Authors: Wenjing Ji; Lihua Zhang; Zhusheng Guo; Shujin Xie; Weiqing Yang; Junjian Chen; Jiamin Wang; Zhiqin Cheng; Xin Wang; Xuehai Zhu; Jianwen Wang; Haiqing Wang; Juan Huang; Ning Liang; David J. McIver
• Keywords: Group B

This study investigated the prevalence of recto-vaginal Group B Streptococcus (GBS) colonization, serotype distribution, and antimicrobial susceptibility patterns among pregnant women in Dongguan, China. Recto-vaginal swabs were collected from at gestational age 35-37 weeks between January 1st 2009 December 31st 2014. Isolates serotyped by latex-agglutination tested against seven antimicrobials disk diffusion. Of 7,726 who completed GBS testing, 636 (8.2%) carriers. 153 isolates available for typing, 6 serotypes (Ia, Ib, III, V, VI VIII) identified with type III being predominant, while 9 (5.9%) non-typable isolates. All sensitive to penicillin, ceftriaxone, linezolid vancomycin, whereas 52.4% resistant clindamycin, 25.9% levofloxacin 64.9% erythromycin. showed colonization Dongguan is significant. Due 100% penicillin all samples, remains first recommendation treatment prevention infection. Susceptibility testing should be performed allergic order choose most appropriate antibacterial agents vertical transmission neonates. In addition, we suggest establishing standard processes culture identification China as early possible.