Dietary acid load and chronic kidney disease in elderly adults: Protein and potassium intake

• DOI: 10.1371/journal.pone.0185069
• Publication Date: 2017-09-27T13:39:46Z
• Authors: Byung-Joon Ko; Yoosoo Chang; Seungho Ryu; Eun Mi Kim; Mi Yeon Lee; Young Youl Hyun; Kyu-Beck Lee
• Keywords: Quartile

Dietary net endogenous acid production (NEAP), which represents total dietary load of nonvolatile acid, may affect kidney function. Estimated NEAP (eNEAP) is calculated indirectly by the ratio protein and potassium intake. A few studies are available assessing association between eNEAP chronic disease (CKD), its relation to intake in elderly.A 1,369 community-dwelling elderly Koreans Kangbuk Samsung Cohort Study (KSCS) were evaluated using a food frequency questionnaire (FFQ) comprehensive health examination. We CKD. also examined their intake.eNEAP was correlated with (r = -0.410, P < 0.001), but not -0.004, 0.879). In full multivariate adjustment for sociodemographic factors, comorbidities, participants higher quartiles (Q2, Q3, Q4) had odds CKD compared lowest quartile (Q1); OR (95% CI) 1.47 (0.78-2.72), 1.66 (0.85-3.23), 2.30 (1.16-4.60) respectively (P trend 0.019). The decreased 0.52 (0.28-0.95), 0.50 (0.26-0.96), (0.21-0.99) 0.050). Protein associated similar subgroup analysis.Dietary Among nutrients related load, negatively CKD, adults.