Reproductive effects of cadmium on sperm function and early embryonic development in vitro

• DOI: 10.1371/journal.pone.0186727
• Publication Date: 2017-11-02T14:02:04Z
• Authors: Li-lin Zhao; Yan-fei Ru; Miao Liu; Jia-nan Tang; Ju-fen Zheng; Bin Wu; Yi-hua Gu; Hui-juan Shi
• Keywords: Toxicant

Cadmium is a major environmental toxicant that released into the atmosphere, water and soil in form of cadmium oxide, chloride, or sulfide via industrial activities, such as manufacturing batteries pigments, metal smelting refining municipal waste incineration. In present study, we investigated effects exposure on sperm quality parameters, fertilization capacity early embryonic development. Our study showed vitro incubation human mouse sperms with for long time (up to 24 hours) could significantly decreased motility concentration- time-dependent manner. Exposure environment short term (30 min) did not affect but reduced rate. We also evaluated at concentrations 0.625 μg/ml, 1.25 μg/ml development observed blastocyst formation rate dramatically increasing concentration. This finding emphasizes hazardous well natural embryo raises greater concerns regarding pollution.