Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma

• DOI: 10.1371/journal.pone.0193910
• Publication Date: 2018-03-21T13:34:07Z
• Authors: Sonali Bose; Karina Romero; Kevin J. Psoter; Frank C. Curriero; Chen Chen; Caroline M. Johnson; Deepak Kaji; Patrick N. Breysse; D’Ann L. Williams; Murugappan Ramana...; William Checkley; Nadia N. Hansel
• Keywords: Atopy; Effect modification

Background Air pollution exposure may contribute to rhinoconjunctivitis morbidity in children with underlying airways disease. Prior studies have not assessed rhinoconjunctivitis-related quality of life (QOL) asthma chronically exposed air pollution. Methods Children ages 9–19 years from peri-urban Peru, self-reporting symptoms (n = 484), were administered the Rhinoconjunctivitis QOL Questionnaire (RQLQ) at repeated intervals over one year, scores dichotomized into bothered (>0) and (= 0). Individual weekly exposures particulate matter<2.5μm (PM2.5) its black carbon (BC) component estimated by inverse distance weighted methods. Generalized estimating equations, adjusting for covariates, associations PM2.5 BC QOL. Results Participants on average 13 old, 55% female, majority atopic (77%). Mean (SD) concentrations 21(3.2) μg/m3 4.4(1.5) μg/m3, respectively. In adjusted multi-pollutant models, each 10μg/m3 increase was associated increased odds worse (OR;[95% CI]: 1.83;[1.33,2.52]). A 10% proportion higher rhinitis burden 1.80;[1.22,2.66]), while increases non-BC PM did significantly impact Associations similar regardless atopy. Conclusion Higher is among asthmatic children.