The effect of lifestyle on late-life cognitive change under different socioeconomic status

• DOI: 10.1371/journal.pone.0197676
• Publication Date: 2018-06-15T10:41:41Z
• Authors: Pei-Hsuan Weng; Jen-Hau Chen; Jeng-Min Chiou; Yu-Kang Tu; Ta-Fu Chen; Ming-Jang Chiu; Sung-Chun Tang; Shin-Joe Yeh; Yen-Ching Chen
• Keywords: Verbal fluency test; Cognitive skill; Cognitive Decline

This study aimed to identify lifestyle factors associated with cognitive change and explore whether the effect of varies by socioeconomic status (SES). Participants aged 65 years older were recruited from elderly health checkup programs 2011 2013 in Taiwan. Neuropsychological tests, including tests global cognition, logical memory, executive function, verbal fluency attention, administered at baseline (N = 603) 2 later 509). After literature review, 9 3 SES indicators chosen their effects on evaluated using linear regression adjusting for age, sex, education, APOE ε4 status, score. Five (high vegetable fish intake, regular exercise, not smoking, light moderate alcohol consumption) [annual household income (> 33,333 USD vs. less), occupational complexity low mental demanding job), education 12 less)] found be protective against decline (P < 0.1 any domains, ß ranging 0.06 0.38). further all factors, higher remained protective. Significant interactions between a healthful (defined as having ≥ factors) changes cognition (Pinteraction 0.02 0.04). The was observed only among participants lower memory [ß 0.17, 95% confidence interval (CI) 0.07–0.26; 0.30, CI 0.14–0.46]. To best our knowledge, this first time explored how affect change. Our findings will aid developing dementia prevention reduce inequalities.