Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera

• DOI: 10.1371/journal.pone.0197760
• Publication Date: 2018-11-01T17:32:42Z
• Authors: Thomas K. Walsh; Nicole Joussen; Kai Tian; Angela McGaughran; Craig J. Anderson; Xinghui Qiu; Seung-Joon Ahn; Lisa Bird; Nena Pavlidi; John Vontas; Jaeeun Ryu; Akhtar Rasool; Isabella Barony M...; Wee Tek Tay; Yongjun Zhang; Mary E. A. Whiteh...; Pierre Jean Silvie; Sharon Downes; Lori Nemec; David G. Heckel
• Keywords: [SDV.SA]Life Sciences [q-bio]/Agricultural sciences; 0301 basic medicine; Insecticides; [SDV]Life Sciences [q-bio]; Lepidoptera genitalia; [SDV.GEN] Life Sciences [q-bio]/Genetics; http://aims.fao.org/aos/agrovoc/c_49865; Moths; Recombinant Protein Production in Mammalian and Insect Cells; AUSTRALIE; PAKISTAN; Gene; 630; GRECE; Agricultural and Biological Sciences; Insecticide Resistance; OUGANDA; Cytochrome P-450 Enzyme System; NOUVELLE ZELANDE; Pyrethrins; BURKINA FASO; pyréthrine de syntèse; ESPAGNE; Recombination, Genetic; Allele; [SDV.SA] Life Sciences [q-bio]/Agricultural sciences; Ecology; Q; R; Insect-Plant Interactions in Agricultural Ecosystems; Life Sciences; Cypermethrin; [SDV] Life Sciences [q-bio]; GHANA; Pyrethroid; PEST analysis; http://aims.fao.org/aos/agrovoc/c_1070; Medicine; http://aims.fao.org/aos/agrovoc/c_3335; http://aims.fao.org/aos/agrovoc/c_7575; Research Article; Biotechnology; cytochrome; SENEGAL; http://aims.fao.org/aos/agrovoc/c_27497; Science; FRANCE; Helicoverpa armigera; 03 medical and health sciences; CHINE; Biochemistry, Genetics and Molecular Biology; Genetics; Animals; INDE; Molecular Biology; Biology; http://aims.fao.org/aos/agrovoc/c_6475; TCHAD; Alleles; 580; Gossypium; [SDV.GEN]Life Sciences [q-bio]/Genetics; résistance aux insecticides; Botany; espèce envahissante; allèle; H10 - Ravageurs des plantes; COREE DU SUD; MADAGASCAR; Pesticide; recombinaison; BRESIL; Molecular Mechanisms of Insect Resistance to Xenobiotics; http://aims.fao.org/aos/agrovoc/c_8724; Genetic Loci; Insect Science; FOS: Biological sciences; CAMEROUN; http://aims.fao.org/aos/agrovoc/c_30255; http://aims.fao.org/aos/agrovoc/c_11794

The cotton bollworm, Helicoverpa armigera (Hübner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This has evolved pyrethroid across its native range and becoming a truly global after establishing in South America having been recently recorded North America. A chimeric cytochrome P450 gene, CYP337B3, identified as mechanism for fenvalerate cypermethrin. Here we show that this common around world with at least eight alleles. It present probably introgressed into closely related sibling species, zea. alleles CYP337B3 are likely have arisen independently geographic locations selection on existing diversity. found Brazil those commonly Asia, suggesting potential origin incursion H. Americas.