Microbiome in the hair follicle of androgenetic alopecia patients
Cabello
DOI:
10.1371/journal.pone.0216330
Publication Date:
2019-05-03T17:26:45Z
AUTHORS (7)
ABSTRACT
Androgenetic alopecia is the most common form of hair loss in males. It a multifactorial condition involving genetic predisposition and hormonal changes. The role microflora during remains to be understood. We therefore analyzed microbiome follicles from patients healthy. Hair were extracted occipital vertex region healthy volunteers further dissected into middle lower compartments. was then characterized by 16S rRNA sequencing. Distinct microbial population found compartment follicles. Middle predominated Burkholderia spp. less diverse; while higher bacterial diversity observed portion. Occipital did not show significant differences. In patients, miniaturized houses elevated Propionibacterium acnes compartments non-miniaturized other regions comparable Increased abundance P. could associated immune response gene expression follicle.
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