Dyslipidemias and cardiovascular risk scores in urban and rural populations in north-western Tanzania and southern Uganda

• DOI: 10.1371/journal.pone.0223189
• Publication Date: 2019-12-06T18:28:42Z
• Authors: Bazil Kavishe; Fiona Vanobberghen; David Katende; Saidi Kapiga; Paula Munderi; Kathy Baisley; Samuel Biraro; Neema Mosha; Gerald Mutungi; Janneth Mghamba; Peter Hughes; Liam Smeeth; Heiner Grosskurth; Robert Peck
• Keywords: Rural population

Background Dyslipidemia is a leading risk factor for atherosclerotic cardiovascular disease. There are few published epidemiological data regarding dyslipidemia in Africa. We determined full lipid and apolipoprotein profiles investigated factors associated with levels urban rural populations of north-western Tanzania southern Uganda. Methods conducted cross-sectional survey randomly-selected, community-dwelling adults (≥18yrs) including five strata per country: one municipality, two district towns areas. Participants were interviewed examined using the World Health Organization STEPwise questionnaire. Serum total cholesterol, low-density lipoprotein high-density triglycerides, apolipoproteins measured. Factors mean assessed by multivariable linear regression. Framingham 10-year scores calculated without lipids. Results One-third study population had dyslipidemia. Low cholesterol affected 32–45% adults. High B found <15% adult all strata, but more common independently higher female gender, older age, education, income, obesity, hypertension. lipids yielded similar results 90% subjects classified as "low risk". Among (>55 years), 30% "high" or "very high" risk. Conclusions Dyslipidemias among Uganda affecting third population. Overall, low high services designed equipped to diagnose treat urgently needed.