Incidence and risk factors for hyperglycemia in pregnancy among nulliparous women: A Brazilian multicenter cohort study

• DOI: 10.1371/journal.pone.0232664
• Publication Date: 2020-05-13T19:35:07Z
• Authors: Bianca F. Nicolosi; Renato T. Souza; Jussara Mayrink; Francisco E. Feitosa; Edilberto A. Roch...; Débora F. Leite; Janete Vettorazzi; Maria H. Sousa; Maria L. Costa; Philip N. Baker; Louise C. Kenny; Jose G. Cecatti; Iracema M. Calderon
• Keywords: Adult; 2. Zero hunger; Science; Incidence; Q; R; 610; Overweight; 3. Good health; Pregnancy Complications; Diabetes, Gestational; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Risk Factors; Hyperglycemia; Medicine; Humans; Female; Brazil; Research Article

Objective To assess the incidence and risk factors for hyperglycemia in pregnancy a cohort of Brazilian nulliparous pregnant women. Materials methods This is secondary analysis multicenter study that enrolled 1,008 women at 19–21 weeks. Exclusion criteria included chronic exposure to corticosteroids previous diabetes. Bivariate multivariate analyses by Poisson regression were used identify associated factors. Results The was 14.9% (150/1,008), 94.7% these cases gestational diabetes mellitus (142/150). Significant family history mellitus, maternal overweight or obesity enrollment, conditions (polycystic ovarian syndrome, thyroid dysfunctions hypertensive disorders). A BMI ≥ 26.3Kg/m2 (RRadj 1.87 [1.66–2.10]) 1.71 [1.37–2.15]) enrollment independent HIP. Conclusions (until weeks gestation) may be as selective markers HIP Given scarcity results women, our findings contribute determine optimal diagnostic approach populations similar socioeconomic characteristics.