Study of reference intervals for free triiodothyronine, free thyroxine, and thyroid-stimulating hormone in an elderly Chinese Han population

• DOI: 10.1371/journal.pone.0239579
• Publication Date: 2020-09-24T17:38:20Z
• Authors: Jingting Xiong; Shiguo Liu; Kai Hu; Yinxiang Xiong; Pengyun Wang; Liang Xiong
• Keywords: Thyroid-stimulating hormone; Free thyroxine; Thyroid peroxidase; Thyroglobulin

The clinical manifestations of thyroid diseases in elderly patients are often atypical. This study aimed to establish reference intervals for function the order help diagnose this population. A total 5345 healthy individuals were examined and divided into three groups according their age: 4297 aged < 65 years (19–64), 719 between 79 years, 329 80 100 years. Levels free triiodothyronine (FT3), thyroxine (FT4), thyroid-stimulating hormone (TSH), peroxidase antibody, thyroglobulin antibody measured these subjects by using a fully automated analyzer. following triiodothyronine, thyroxine, obtained from each age group: For (19–64 years), FT3, FT4, TSH 3.40–6.44, 10.26–19.25 pmol/L 0.50–4.81 μIU/mL, respectively. FT4 ranged 3.01–5.91, 10.04–19.76 pmol/L, 0.54–5.51 varied 2.82–5.57, 9.79–21.22 0.31–6.28 μIU/mL FT3 concentration was lower concentrations higher ≥ than those <65 (P<0.0001; P = 0.0039; P<0.0001, respectively). In conclusion, establishment interval would allow clinicians more accurately easily.