Measurement properties of the one-minute sit-to-stand test in children and adolescents with cystic fibrosis: A multicenter randomized cross-over trial

• DOI: 10.1371/journal.pone.0246781
• Publication Date: 2021-02-12T21:25:00Z
• Authors: Yann Combret; Fairuz Boujibar; Charlotte Gennari; Clément Medrinal; Sophie Sicinski; Tristan Bonnevie; Francis-Edouard G...; Muriel Laurans; Christophe Marguet; Pascal Le Roux; Bouchra Lamia; Guillaume Prieur; Grégory Reychler
• Keywords: Repeatability

Background Functional exercise capacity assessment is recommended in children with cystic fibrosis (CF). The six-minute walk test (6MWT) a valid evaluation of but can be technically complex. Inversely, the sit-to-stand (STST) simple method to evaluate capacity, and validated healthy adults CF. This study aimed STST measurement properties adolescents Methods In this multicenter study, CF (6 18 years) performed two iterations both 6MWT randomized order. Criterion validity was determined by assessing correlations between repetitions distance (6MWD). Intra-rater reliability, test-retest repeatability, mean bias limits agreement were also assessed. Relationships other outcomes (i.e. respiratory quadriceps muscle strength) cardio-respiratory responses analysed for tests. Results Thirty-six included (mean age 12.0 ±3.5 years FEV1 95.8 ±25.0%). On average, 39.6 ±10.5 during 6MWD 596.0 ±102.6 meters. number significantly correlated (r = 0.48; p<0.01). Both tests had very good intra-rater reliability (ICC 0.91 (95%CI 0.76–0.96) ICC 0.94 0.85–0.97)), significant learning effect. not or strength test, induced fewer than 6MWT. Conclusions an easy-to-use functional moderate criterion when compared CF, probably because measure different components capacity. useful unfeasible, however further investigations are required explore clinical implications results Clinical trial registration NCT03069625 .