Low skeletal muscle radiodensity is the best predictor for short-term major surgical complications in gastrointestinal surgical cancer: A cohort study

• DOI: 10.1371/journal.pone.0247322
• Publication Date: 2021-02-20T02:53:51Z
• Authors: Ana Lúcia Miranda...; Maria Cristina Go...; Iasmin Matias de ...; Isabel Pinto Amor...; Galtieri Otavio C...; Marília Nelo Oliv...; Jeane Cristina Al...; Ana Paula Trussar...
• Keywords: Male; Sarcopenia; Science; 610; Nutritional Status; colorectal cancer; radiodensity; 03 medical and health sciences; Postoperative Complications; 0302 clinical medicine; Risk Factors; Gastric; 616; Humans; Prospective Studies; Muscle, Skeletal; Aged; Gastrointestinal Neoplasms; 2. Zero hunger; Q; R; Length of Stay; Middle Aged; 3. Good health; Medicine; Female; Neoplasm Grading; Tomography, X-Ray Computed; Research Article

The aim of this study was to evaluate whether body composition, muscle function, and their association are predictive factors for short-term postoperative complications in patients with gastric colorectal cancer. A prospective cohort conducted undergoing resection tumors. Nutritional status assessed using Patient-Generated Subjective Global Assessment (PG-SGA) anthropometric techniques. Low handgrip strength (HGS) observed when <16kg women, <27kg men. Computed tomography images were used measure visceral adipose tissue, skeletal index (SMI), radiodensity (SMD). Complications grade II or above (according Clavien-Dindo’s classification) considered a follow-up period up 30 days after surgery. Major defined they reached III above. total 84 analyzed (57.1% female, 59.7 ± 12.6 years) 19% diagnosed low HGS + SMI SMD. Postoperative occurred 51.2%, these presented significantly longer duration surgery hospital stay. 16.7% the number patients. Binary logistic regression adjusted by age, sex, tumor staging showed that SMD, obesity independent risk complications, but only SMD an factor major complications. is following