Brain correlates of speech perception in schizophrenia patients with and without auditory hallucinations

• DOI: 10.1371/journal.pone.0276975
• Publication Date: 2022-12-16T18:26:01Z
• Authors: Joan Soler-Vidal; Paola Fuentes-Cla...; Pilar Salgado-Pineda; Nuria Ramiro; María Ángeles Gar...; María Llanos Torres; Antonio Arévalo; Amalia Guerrero-P...; Josep Munuera; Salvador Sarró; Raymond Salvador; Wolfram Hinzen; Peter McKenna; Edith Pomarol-Clotet
• Keywords: Auditory hallucination; Temporal cortex; Superior temporal gyrus; Auditory perception; Gyrus

The experience of auditory verbal hallucinations (AVH, “hearing voices”) in schizophrenia has been found to be associated with reduced cortex activation during perception real stimuli like tones and speech. We re-examined this finding using 46 patients (23 frequent AVH 23 hallucination-free), who underwent fMRI scanning while they heard words, sentences reversed Twenty-five matched healthy controls were also examined. Perception speech all elicited the bilateral superior temporal cortex, inferior lateral prefrontal parietal supplementary motor area controls. During sentence conditions, as a group showed left primary (Heschl’s gyrus) relative No differences between without any condition. This study therefore fails support previous findings that attenuates speech-perception-related brain activations cortex. At same time, it suggests patients, regardless presence AVH, show perception, which could reflect an early information processing deficit disorder.