Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement

• DOI: 10.1371/journal.pone.0278996
• Publication Date: 2022-12-21T18:29:45Z
• Authors: Danielle Ramsey; Gita Ramdharry; Mariacristina Scoto; Francesco Muntoni; Amanda Wallace
• Keywords: Inter-Rater Reliability; Bland–Altman plot; Intra-rater reliability

The Revised Hammersmith Scale (RHS) for Spinal Muscular Atrophy (SMA) was designed as a psychometrically robust clinical outcome assessment to assess physical abilities of patients with type 2 and 3 SMA. reliability properties the RHS have not yet been reported. A prospective study undertaken in UK cohort experienced neuromuscular paediatric Physiotherapists. Reliability testing conducted via virtual survey platform two weeks apart. Through participants scored videos assessments, one child SMA 3. Inter intra-rater analysed using Intraclass Correlation Coefficient (ICC). Intra-rater agreement further Bland Altman (BA) Limits Agreement (LOA) plots. acceptable inter variability set change ± by international team expert physiotherapists who developed RHS. Inter-rater agreement, n = 22 raters, ICC 0.989 (95% CI 0.944 1.00), 97.7% scores were within limits points. 21 ranged from 0.922 1.0, 97.6% mean difference -0.10 (-0.6 0.4), lower LOA -2.24 upper +2.04. between tests -0.05 0.5), -2.48 +2.38. scoring precision fell BA ±2 results demonstrate that is highly reliable when used physiotherapists, test regarding confirmed lie