Impact of early nutrition and feeding route on clinical outcomes of neurocritically ill patients

• DOI: 10.1371/journal.pone.0283593
• Publication Date: 2023-03-23T18:19:10Z
• Authors: Young Kyun Choi; Hyun-Jung Kim; Joonghyun Ahn; Jeong-Am Ryu
• Keywords: Clinical nutrition; Clinical endpoint

Early proper nutritional support is important to critically ill patients. Nutritional also associated with clinical outcomes of neurocritically We investigate whether early nutrition in This was a retrospective, single-center, observational study including neurosurgical patients who were admitted the intensive care unit (ICU) from January 2013 December 2019. Patients started enteral or parenteral within 72 hours after ICU admission defined as group. The primary endpoint in-hospital mortality. secondary an infectious complication. Propensity score matching (PSM) and propensity weighting overlap weights (PSOW) used control selection bias confounding factors. Among 1,353 patients, performed 384 (28.4%) patients: 152 (11.2%) (EEN) 232 (17.1%) (EPN). In overall population, rate mortality higher late than those (P<0.001). However, there no significant difference complications incidence between groups PSM PSOW adjusted population (all P>0.05). EEN had low compared EPN (P<0.001 P = 0.001, respectively). multivariable analysis overall, adjusted, association P>0.05), but significantly P<0.05). Eventually, may reduce risk