Long-term prognosis after coronary bifurcation PCI—A nationwide observational study

• DOI: 10.1371/journal.pone.0317628
• Publication Date: 2025-03-26T19:59:27Z
• Authors: András Katona; Sacharias von Koch; Pontus Andell; Sebastian Völz; Elmir Omerovic; Ole Fröbert; Moman A. Mohammad
• Keywords: Mace

Background Long-term outcomes of percutaneous coronary intervention (PCI) for bifurcation lesions are underexplored. We investigated long-term PCI proximal LAD involving D1. Methods Using Swedish registries, we included all patients undergoing LAD-D1 with drug-eluting stents between 2010 and 2020. Patients were stratified into two groups: simple complex PCI. The group those in the only, while involved kissing balloon technique or a 2-stent approach A multivariable Cox regression model was used to estimate event rates major adverse clinical events (MACE), defined as all-cause death new myocardial infarction. Secondary target segment revascularization artery by-pass graft surgery (CABG) definite stent thrombosis. Results total 6,796 individuals analyzed: 2,007 underwent 4,789 Baseline characteristics comparable groups. slightly younger, more often male, frequently taking statins. At 1-year, MACE lower (6.2% vs 7.9%; adjusted HR 0.74, 95% CI 0.59-0.93, p = 0.010). result driven by mortality (3.6% vs. 5.0%; 0.73, 0.54-0.98, 0.036). No significant differences infarction, revascularization, CABG, thrombosis, stroke, bleeding observed groups, persisting at five years. Conclusion Over five-year period, LAD/D1 associated better outcome than routine setting.