Incisional Negative Pressure Wound Therapy devices applied after Total Ankle Arthroplasty: A Hospital-Based Health Technology Assessment

Negative-pressure wound therapy
DOI: 10.1371/journal.pone.0322327 Publication Date: 2025-04-29T17:35:02Z
ABSTRACT
A portable, single-use incisional Negative Pressure Wound Therapy (iNPWT) device could be used directly on the wound incision following Total Ankle Arthroplasty (TAA). In order to support local decision-making in a French university hospital for adoption of such this indication, three-dimensional (clinical, economic and organizational) Hospital Based-Health Technology Assessment (HB-HTA) was conducted. The HB-HTA based on: literature review; results from PICO-PTC single-site randomized controlled trial (ClinicalTrial.gov identifier NCT03886818); semi-structured interviews with healthcare professionals. Two comparative retrospective cohort studies were retrieved review. They suggested decreased incidence healing complications iNPWT compared standard dressings, although no difference found study. There significant study Medicine-Surgery-Obstetrics costs between two strategies: €10,639.65 [CI 95% (7,997.45; 17,988.68)] group versus €9,672.59 (7,966.29; 13,393.65)] dressings group. Adoption prophylactic strategy would result an approval pay 1.5% supplement hospitalization costs. It also improve professionals' workflow, facilitate monitoring nurses orthopedic departments dressings. clinical effectiveness portable not demonstrated use, terms complications, patients scheduled TAA selected basis risk factors. However, as may bring organizational benefits has been associated costs, made according surgeon's expertise, instance patient's factors complications.
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