Intrauterine Fetal Growth Restriction and Oligohydramnios of Undetermined Etiology

• DOI: 10.1373/jalm.2016.021238
• Publication Date: 2018-07-23T22:26:05Z
• Authors: Daniel Fernando G...; Whitney Neufeld-K...; Sheila Weiss; Yajuan J Liu; Kimberly K Ma; Corinne L Fligner; Christina M Lockwood
• Keywords: Amniocentesis; Intrauterine growth restriction

A 32-year-old G3P2002 (3 pregnancies, 2 births at full term, 0 preterm, abortions, still living) pregnant woman of Filipino ancestry was referred to a tertiary institution for severe intrauterine growth restriction (IUGR)4 20 weeks' gestation. Ultrasound showed fetal size uniformly less than expected, with measurements <1% age, small chest, echogenic bowel, thickened nuchal fold, enlarged cisterna magna, and oligohydramnios.

The obstetric history relevant healthy children different partner. The father the current pregnancy also had There no medication or drug history, thyroid function tests were normal. patient Rh-positive, negative antibody screen cystic fibrosis carrier screen. Maternal serum quad (α-fetoprotein, estriol, human chorionic gonadotropin, inhibin A) aneuploidy indicated low risk. complete blood count included hematocrit 33%, hemoglobin 10.8 g/dL (reference range 11.5–15.5), mean corpuscular volume 60 fL 81–98). Prenatal records that this normal values, although original test results not available.

Diagnostic amniocentesis amniotic fluid α-fetoprotein gestational PCR cytomegalovirus (CMV) toxoplasmosis negative. Interphase …