Digital Screening for Cognitive Impairment — A Proof of Concept Study

• DOI: 10.14283/jpad.2021.2
• Publication Date: 2021-02-04T10:22:43Z
• Authors: Victor Bloniecki; G. Hagman; M. Ryden; M. Kivipelto
• Keywords: Montreal Cognitive Assessment; Memory clinic; Cognitive test

Background: Due to an ageing demographic and rapid increase of cognitive impairment dementia, combined with potential disease-modifying drugs other interventions in the pipeline, there is a need for development accurate, accessible efficient screening instruments, focused on early-stage detection neurodegenerative disorders. Objective: In this proof concept report, we examine validity newly developed digital test, Geras Solutions Cognitive Test (GCST) compare its accuracy against Montreal Assessment (MoCA). Methods: 106 patients, referred memory clinic, Karolinska University Hospital, due complaints were included. All patients assessed presence disorder accordance standard investigative procedures. 66% diagnosed subjective (SCI), 25% mild (MCI) 9% fulfilled criteria dementia. administered both MoCA GSCT. Descriptive statistics specificity, sensitivity ROC curves established test. Results: Mean score differed significantly between all diagnostic subgroups GSCT (p<0.05). total test time Overall, showed 0.88 specificity 0.54 at cut-off <=26 while displayed 0.91 0.55 respectively <=45. Conclusion: This report suggests that viable instrument MCI