Five-Minute Cognitive Test as A New Quick Screening of Cognitive Impairment in The Elderly

• DOI: 10.14336/ad.2019.0115
• Publication Date: 2019-11-16T15:17:39Z
• Authors: Jie Zhang; Lijun Wang; Xia Deng; Guoqiang Fei; Lirong Jin; Xiaoli Pan; Liuhan Cai; Anthony D Albano; Chunjiu Zhong
• Keywords: Verbal fluency test; Equating; Cognitive test

This study aims to develop a new evaluation method for quickly and conveniently screening cognitive impairment in the elderly. The five-minute test (FCT) was designed capture deficits five domains of abilities, including episodic memory, language fluency, time orientation, visuospatial function, executive function. Subsequently, FCT efficiencies differentiating normally ability from were explored compared with that Mini-Mental Status Evaluation (MMSE). Equipercentile equating utilized create crosswalk between scores MMSE. Further, association MMSE hippocampal volumes investigated. There 241 subjects aged 60 years or above enrolled this study, 107 adults abilities normal range, patients mild (MCI), 27 Alzheimer disease (AD). AUC detection (MCI AD) 0.885 (95% CI 0.838 0.922). sensitivity specificity diagnosis 80.6% 84.11 %, respectively. FCT's diagnostic performance superior same cohort. Mean completion 339.9 ± 67.7 seconds (5-6 min). In addition, conversion table on created. positively correlated volumes. is novel, reliable, valid dementia at early stages.