Emphysematous Pyelonephritis: A Correlation of Clinical Characteristics With Serum Parameters and Its Contribution in Determination of Prognostic Factors

• DOI: 10.14740/cii.v3i1.41
• Publication Date: 2018-04-01
• Authors: Rajeev T.P; Yashasvi Singh; Sasanka Kumar Barua; Debanga Sarma; Manash Pratim Kas...
• Keywords: Hypoalbuminemia; Bacteremia; Microbiological culture

Background: Emphysematous pyelonephritis (EPN) is a severe life-threatening infection of renal parenchyma, peri-renal tissue and collecting system primarily caused by gas forming bacteria carries significant mortality 80% when treated non-surgically. Early identification the disease process along with timely surgical management paramount significance. In last 2 decades evolution has lead to substantial decrease in up 21%. The focus present study was investigate optimal serum panel parameters propagate prognostic model for evaluation EPN. Methods: conducted at Department Urology GMCH, Gauhati. Authors retrospectively analyzed all clinical, laboratory radiological data outcome 44 patients EPN from January 2015 August 2017. Chi-square analysis Spearman tests were used carve out association correlation. Results: overall survival rate 86.37% (38/44). Escherichia coli ( E.Coli ) most common bacterial pathogen isolated urine pus culture. Uncontrolled type diabetes mellitus (DM), polymicrobial infection, shock, thrombocytopenia, bacteremia, hypoalbuminemia, hemodialysis significantly more cases death correlated adverse profile. AUC ROC curve seven factors 0.59 only thrombocytopenia (TCP) (AUC = 0.78, P 0 .033) liver cirrhosis 0.76, 0.018) came be post analysis. Conclusions: Upfront clinical such as uncontrolled DM 2, altered are Clin Infect Immun. 2018;3(1):1-8 doi: https://doi.org/10.14740/cii41w