Crude extract of Stryphnodendron adstringens (Mart.) Coville: antifungal, antibacterial, antioxidant and hemolytic activities

• DOI: 10.14808/sci.plena.2025.029901
• Publication Date: 2025-03-22T13:07:11Z
• Authors: Túlio Custódio Reis; Carolina Passarel...; Luiz Francisley ...; Valter Henrique ...; Francisco Eduardo...; Rodrigo Machado ...

The search for bioactive plant compounds has gained significant attention worldwide in recent decades. Stryphnodendron adstringens (Mart.) Coville, commonly known as barbatimao, is endemic to the Brazilian cerrado and characterized by a high phenolic content its bark, which possesses potential biological activity. This study aimed evaluate antibacterial, antifungal, hemolytic activities of hydroethanolic extract (EHE) S. using disk diffusion method. Additionally, it sought quantify polyphenols Folin-Ciocalteu method, flavonoids through complexation reaction with aluminum chloride, assess antioxidant activity DPPH radical scavenging. exhibited relative concentration (373.23 mg EAG/g) flavonoid (961.96 EQ/g). showed above 70%. At 100 µg/mL, satisfactory antimicrobial was observed against Escherichia coli, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, Candida albicans, glabrata, krusei, parapsilosis, Cryptococcus neoformans var. grubii. no Therefore, can be inferred that exhibits activity, possibly attributed rich content.