Sex differences in the response to resistance exercise training in older people

• DOI: 10.14814/phy2.12834
• Publication Date: 2016-06-29T14:02:10Z
• Authors: Mariasole Da Boit; Rachael Sibson; Judith R. Meakin; Richard M. Aspden; Frank Thies; Arduino A. Mangoni; Stuart Robert Gray
• Keywords: Blood Glucose; Male; Aging; 570; 610; R Medicine; Muscle adaptation; 796; 03 medical and health sciences; Sex Factors; 0302 clinical medicine; Humans; Insulin; Muscle, Skeletal; 10. No inequality; Triglycerides; Original Research; Aged; exercise; Interleukin-6; Tumor Necrosis Factor-alpha; aging; BB/J015911/1; R; muscle adaptation; Resistance Training; Adaptation, Physiological; Torque; ageing; sexual dimorphism; Biotechnology and Biological Sciences Research Council (BBSRC); Female

Resistance exercise training is known to be effective in increasing muscle mass older people. Acute measurement of protein metabolism data has indicated that the magnitude response may differ between sexes. We compared adaptive responses and function 18 weeks resistance a cohort (>65 years) men women. improved knee extensor maximal torque, 4 m walk time, time complete five chair rises, anatomical cross-sectional area (ACSA) quality with no effect on fat/water ratio or plasma glucose, insulin, triacylglycerol, IL-6, TNF-α. Differences sexes were observed for torque greater increases versus women (P < 0.05). Maximal increased by 15.8 ± 10.6% 41.7 25.5% men, whereas 8.8 17.5% 33.7 25.6% men. In conclusion, this study demonstrated difference adaptation, some outcome measures employed, The mechanisms underlying observation remain established.