The effects of resistance training on bone mineral density and bone quality in type 2 diabetic rats

• DOI: 10.14814/phy2.14046
• Publication Date: 2019-03-27T18:12:39Z
• Authors: Aoi Ikedo; Kohei Kido; Satoru Ato; Koji Sato; Ji‐Won Lee; Satoshi Fujita; Yuuki Imai
• Keywords: Male; Bone quality; Time Factors; Physiology; Rats, Inbred OLETF; Electric Stimulation Therapy; 03 medical and health sciences; Bone Density; QP1-981; Animals; Rats, Long-Evans; Type-2 diabetes mellitus; Original Research; 0303 health sciences; Tibia; type‐2 diabetes mellitus; type-2 diabetes mellitus; Resistance Training; bone quality; Resistance training; Bone mass; Disease Models, Animal; Diabetes Mellitus, Type 2; Bone Remodeling; resistance training

Resistance training (RT) has been known to be effective in maintaining and improving bone strength, which is based on mineral density (BMD) quality. However, it not clear whether RT strength patients with type-2 diabetes mellitus (T2DM), who have a high risk of fracture. Therefore, we tested the effects 6-week regimen using percutaneous electrical stimulation T2DM model rats, male Otsuka Long-Evans Tokushima Fatty (OLETF), its control, (LETO). After 6 weeks RT, tibial BMD legs was significantly higher than that control (CON) both groups. In diaphyseal cortical bone, area/tissue area, thickness increased compared CON Cortical porosity highly observed OLETF LETO, but improved Interestingly, trabecular number, space as well volume/tissue volume proximal metaphyseal were contrast, connectivity structural index affected by RT. These results indicate effectively quality rats rats. may potential improve reduce fracture risk, even T2DM.