Fractionated free fatty acids and their relation to diabetes status after Roux‐en‐Y gastric bypass: A cohort study

• DOI: 10.14814/phy2.14708
• Publication Date: 2021-01-19T12:03:23Z
• Authors: Freja Eriksen; Elin R. Carlsson; Jens K. Munk; Sten Madsbad; Mogens Fenger
• Keywords: Gastric bypass surgery; Roux-en-Y anastomosis

Bariatric surgery is associated with near-immediate remission of type 2 diabetes and recently suggested as a treatment for diabetes. Specifically, Roux-en-Y gastric bypass has been focus much research, but still, the mechanisms action are only partly elucidated. We aim to investigate whether some might be mediated by free fatty acids (FFAs). measured eight fractionated FFAs before up years after in 207 patients, divided into three groups. One non-diabetic group, one diabetic group post-operative persistent surgery. Pre- postoperative levels were compared within between The sum lower diabetes, other pre-surgery level linoleic acid was significantly two decreased from months surgery, except oleic arachidonic Docosahexaenoic (DHA) group. decreasing post-surgery all precursors acid, DHA, respectively, which may imply drift, indicating that they need sustained at an acceptable optimal metabolic function. fact suggest this represent distinct types It proposed could used biomarker determine plausibility