Papillary thyroid carcinoma with desmoid-type fibromatosis: A clinical, pathological, and immunohistochemical study of 14 cases

• DOI: 10.1507/endocrj.ej17-0242
• Publication Date: 2017-08-09T22:09:48Z
• Authors: Nami Takada; Mitsuyoshi Hirokawa; Masahiro Ito; Aki Ito; Ayana Suzuki; Miyoko Higuchi; Seiji Kuma; Toshitetsu Hayashi; Masao Kishikawa; Shuichi Horikawa; Akira Miyauchi
• Keywords: Nodular fasciitis; Tissue microarray; Thyroglobulin

PAPILLARY THYROID CARCINOMA (PTC) has many morphologic variants.PTC can present with extensive proliferation of fibroblasts and myofibroblasts in the stroma.This variant is extremely rare been described terms "PTC exuberant nodular fasciitis-like stroma" [1], [2], fibromatosis-like [3], forming a myofibroblastic tumor" [4].Recently, Rebecchini et al. proposed that should be renamed PTC desmoid-type fibromatosis (DTF) because mesenchymal component showed aberrant nuclear cytoplasmic immu-