Upper Airway Narrowing during Central Apnea in Obese Adolescents

• DOI: 10.1513/annalsats.201806-412oc
• Publication Date: 2018-10-29T15:18:42Z
• Authors: Roberta M. Kato; Yoon-Chul Kim; Biswas Joshi; Shirleen Loloyan; Choo Phei Wee; Ziyue Wu; Winston H. Tran; Thomas G. Keens; Michael C. K. Khoo; Krishna S. Nayak; Sally L. Davidson...
• Keywords: Central sleep apnea

The use of real-time magnetic resonance imaging (MRI) for the evaluation during sleep-related respiratory events can lead to better understanding airway dynamics.To investigate dynamic anatomy upper central apnea.The study included obese adolescents who snore and were otherwise healthy. Subjects underwent an overnight baseline polysomnogram. slept a 24-minute MRI scan wearing full face mask attached pneumotach. Sleep versus wakefulness was inferred from heart rate patterns. Central apneas scored using tracings facemask airflow abdominal bellows. cross-sectional area before, during, after each apnea event recorded.Eight subjects studied 57 observed scanning natural sleep. median age 14.0 years (interquartile range [IQR], 13.5 15.5). average reduction in -38% (IQR, -27 -51) primary snorers -45% -40 -54) with obstructive sleep apnea. percentage decrease positively correlated length (ρ = 0.389; r2 0.152; P 0.003).We that there is narrowing adolescent subjects, MRI.