COVID-19 infections are also affected by human ACE1 D/I polymorphism

0303 health sciences Polymorphism, Genetic Haptoglobins SARS-CoV-2 Vitamin D-Binding Protein Pneumonia, Viral COVID-19 Complement C3 Peptidyl-Dipeptidase A 3. Good health Betacoronavirus 03 medical and health sciences INDEL Mutation Prevalence Humans Coronavirus Infections Hemochromatosis Protein Pandemics
DOI: 10.1515/cclm-2020-0425 Publication Date: 2020-04-17T13:15:09Z
ABSTRACT
The number of victims of the COVID-19 pandemic shows important geographical differences. In this study, a number of human genetic polymorphisms were compared to the number of Covid-19 patients and Covid-19 mortality. Data from 33 countries were analyzed. Among the polymorphisms tested, the human angiotensine converting enzyme (ACE) polymorphism turned out to be a determinant factor in both prevalence and mortality. The present findings may partly explain why some countries are more affected than others by the Covid-19 pandemic.
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