COVID-19 infections are also affected by human ACE1 D/I polymorphism

• DOI: 10.1515/cclm-2020-0425
• Publication Date: 2020-04-17T13:15:09Z
• Authors: Joris R. Delanghe; Marijn M. Speeckaert; Marc L. De Buyzere
• Keywords: Pandemic; 2019-20 coronavirus outbreak

To the Editor,The outbreak of COVID-19 pandemic shows a marked geographical variation in its prevalence and mortality.As no viral mutations have been reported, which can explain important variations, question arises if genetic host may affect outcome infection.We therefore postulated that variability genotype distribution number immune-related human plasma proteins showing [1-3] might partly variable infection.Prevalence mortality data (per 1,000,000 inhabitants) infection from European, North-African Middle East countries were included study: Algeria, Austria, Belgium, Bulgaria, Cyprus, Croatia, Czech