SYNTHESIS AND ANTIVIRAL ACTIVITY OF NEW 4- (PHENYLAMINO)THIENO[2,3-b]PYRIDINE DERIVATIVES

• DOI: 10.1515/hc.2004.10.6.407
• Publication Date: 2011-05-04T13:05:19Z
• Authors: Alice M. R. Berna...; Luiz C. S. Pinheiro; Vitor Francisco F...; Alexandre R. Azevedo
• Keywords: 01 natural sciences; 0104 chemical sciences

Several new 4-(phenylamino)thieno [2,3-f>]pyridines (6a-e) were synthesized and tested against herpes simplex virus type 1 (HSV-1).For the first time one compound (6a) of this heterocyclic system showed 86% inhibitory indicating that these compounds retain antiviral potency in comparison to parent pirazolo-pyridine derivatives. 5