Curcumin Stimulates Biochemical Mechanisms of Apis Mellifera Resistance and Extends the Apian Life-Span

• DOI: 10.1515/jas-2015-0014
• Publication Date: 2015-06-02T18:21:57Z
• Authors: Aneta J. Strachecka; Krzysztof Olszewski; Jerzy Paleolog
• Keywords: 0301 basic medicine; proteolysis; 03 medical and health sciences; antioxidant; apis mellifera; QL1-991; nosema spp.; dna methylation; Zoology; vitality; 3. Good health

Abstract We examined the influence of curcumin-supplemented feeding on worker lifespan, Nosema resistance, key enzyme activities, metabolic compound concentrations and percentage global DNA methylation. Two groups (Apis mellifera) were set up: 1) control group; workers fed ad libitum with sucrose syrup; 2) syrup addition curcumin. Dead removed every two days spp. infection levels assessed. Hemolymph was taken from living for biochemical analyses. The methylation level analysed using heads thoraces. bees that consumed curcumin lived longer less infested curcumin-treated had higher proteins, non-enzymatic biomarkers (triglycerides, glucose, cholesterol, Mg 2+ Ca ), uric acid creatinine, as well elevated activities antioxidant enzymes (SOD , GPx, CAT GST neutral proteases, protease inhibitors, enzymatic (AST ALT ALP ). albumin urea, acidic alkaline proteases in group. Curcumin decreased especially older which natural, age-related increase observed. Most parameters increased over apian youth adulthood, bees. decrease markedly delayed appeared to be an unexpectedly effective natural bio-stimulator, improving health vitality. This multifactorial effect is caused by activation many processes involved formation resistance.