Insecticidal effect of new synthesized chalcone derivatives on Caribbean fruit fly, Anastrepha suspensa

• DOI: 10.1515/znc-2024-0005
• Publication Date: 2024-05-02T10:03:40Z
• Authors: Sümeyye Yücetepe; Bedia Koçyiğit-Ka...; Xiangbing Yang; Nurhayat Tabanca; Fatih Tok
• Keywords: Chalcone; On the fly

Abstract In this present study, new chalcone derivatives were synthesized from 4-aminoacetophenone, which confirmed by spectroscopic methods. The toxic risks of chalcones to humans and the environment investigated a web-based platform called ADMETlab. With program, possible effects compounds on liver, respiratory system, eyes evaluated. For topical insecticidal activity, adult female Caribbean fruit fly, Anastrepha suspensa , was targeted. Results toxicity tests showed that are effective against A. . Among chalcones, 1-(4-cinnamoylphenyl)-3-( p -tolyl)urea ( 2 ) exhibited greatest resulting in 73 % mortality at 100 µg/fly after 24 h, whereas other less than 30 mortality. Our results demonstrate activity may be modulated presence certain phenyl ring structure derivative and, therefore, has potential for design efficient chemicals tephritid fly management.